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Updated: Apr 26, 2026
12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
9.9K
[Gabapentin-induced cutaneous leukocytoclastic vasculitis]
Slaheddine Rached1, Raoudha Slim1, Neila Fathallah1
1Laboratoire de pharmacologie, Faculté de médecine, Sousse, Tunisie.
Therapie
|July 23, 2014
Summary
A woman developed cutaneous leukocytoclastic vasculitis after taking gabapentin. This case highlights a potential adverse drug reaction to gabapentin, emphasizing the need for vigilance in clinical practice.
Area of Science:
- Dermatology
- Pharmacology
- Pathology
Background:
- Gabapentin is an anticonvulsant and analgesic medication.
- Cutaneous leukocytoclastic vasculitis is an inflammation of small blood vessels in the skin.
Observation:
- A case study of a female patient is presented.
- The patient developed a skin condition following gabapentin treatment.
Findings:
- The patient was diagnosed with cutaneous leukocytoclastic vasculitis.
- The vasculitis was temporally associated with gabapentin therapy.
Implications:
- This case suggests a potential link between gabapentin and leukocytoclastic vasculitis.
- Clinicians should consider gabapentin as a possible cause of vasculitis in patients presenting with compatible symptoms.
- Further research may be warranted to establish causality and understand the underlying mechanisms.
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