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Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia.

M Föcking1, L M Lopez1, J A English1

  • 1Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.

Molecular Psychiatry
|July 23, 2014
PubMed
Summary

This study identified over 140 differentially expressed proteins in the postsynaptic density (PSD) of schizophrenia patients, highlighting roles for endocytosis and NMDA-interacting proteins in disease pathophysiology.

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