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Updated: Apr 26, 2026

Improved UPLC-UV Method for the Quantification of Vitamin C in Lettuce Varieties Lactuca sativa L. and Crop Wild Relatives Lactuca spp.
Published on: June 30, 2020
Cattle can produce vitamin C (VC), but plasma VC levels vary. Supplementing VC may benefit cattle experiencing stress or illness, with proposed reference ranges for Japanese Black cattle.
Area of Science:
- Veterinary Medicine
- Animal Nutrition
- Biochemistry
Background:
- Ruminants, including cattle, synthesize vitamin C (VC) endogenously.
- Dietary VC requirements in cattle are not well-established.
- Plasma VC levels in cattle are variable and influenced by physiological and pathological conditions.
Purpose of the Study:
- To review methods for determining plasma VC concentration in cattle.
- To discuss VC nutrition and supplementation efficacy in various cattle categories.
- To propose a reference range for plasma VC in Japanese Black cattle.
Main Methods:
- Literature review of studies on plasma VC determination in cattle.
- Analysis of factors affecting plasma VC levels (heat stress, disease).
- Evaluation of VC supplementation trials in calves, dairy, and beef cattle.
Main Results:
- Plasma VC concentration is affected by heat stress, hepatic lesions, fattening, and diseases like mastitis.
- Existing methods for plasma VC determination yield variable results in bovines.
- VC supplementation may be beneficial for cattle with depleted plasma VC.
Conclusions:
- Plasma VC levels serve as an indicator of health status in cattle.
- Further research is needed to establish optimal VC supplementation strategies.
- A reference range for plasma VC in Japanese Black cattle is proposed to aid in health assessment.
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