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Updated: Apr 26, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa
Albert Lin1, Athena Poppas, Atizaz Mansoor
1aDepartment of Medicine bDepartment of Medicine, Division of Cardiology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island, USA.
Abstract:
A pseudoaneurysm of the mitral-aortic intervalvular fibrosa is a rare but potentially fatal complication seen primarily in the context of infective endocarditis. In this study, we discuss a case of infective endocarditis that was complicated by the rupture of a pseudoaneurysm of the mitral-aortic intervalvular fibrosa. We review the salient echocardiographic findings of this clinical condition.
Insights
A rare complication of infective endocarditis, pseudoaneurysm of the mitral-aortic intervalvular fibrosa can rupture. This case highlights key echocardiographic findings for diagnosing this potentially fatal condition.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (MAIVF) is a rare but life-threatening complication.
- It is most frequently associated with infective endocarditis.
- Rupture of MAIVF pseudoaneurysms can lead to severe hemodynamic compromise.
Observation:
- This study presents a case of infective endocarditis complicated by a ruptured pseudoaneurysm of the mitral-aortic intervalvular fibrosa.
- The case underscores the importance of recognizing this specific complication.
Findings:
- The study reviews salient echocardiographic findings associated with pseudoaneurysms of the mitral-aortic intervalvular fibrosa.
- Echocardiography is crucial for identifying and characterizing these pseudoaneurysms.
Implications:
- Early diagnosis and management of infective endocarditis-related pseudoaneurysms are critical for patient outcomes.
- Understanding echocardiographic features aids in timely intervention for this rare but severe condition.
Related Concept Videos
Mitral Stenosis I: Introduction
Aneurysm I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Regurgitation I: Introduction
Aneurysm III: Interprofessional Care
Mitral Valve Prolapse II: Assessment and Management

