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Updated: Apr 26, 2026

The Drosophila Imaginal Disc Tumor Model: Visualization and Quantification of Gene Expression and Tumor Invasiveness Using Genetic Mosaics
Published on: October 6, 2016
Tumor models: tumor-stroma interactions drive neoplastic transformation in Drosophila
1ICREA and Institute for Research in Biomedicine, Parc Cientific de Barcelona, Baldiri Reixac, 10-12, 08028 Barcelona, Spain.
Abstract:
Stromal cells play a supportive role in the initiation and progression of carcinomas. A new study in Drosophila implicates mesenchymal cells in supporting EGF receptor-driven tumor growth and cellular transformation of epithelial tissues.
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