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Updated: Apr 26, 2026
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Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
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New imaging techniques for nonmuscle invasive bladder cancer
Friedrich-Carl von Rundstedt1, Seth P Lerner
1Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA.
Current Opinion in Urology
|July 23, 2014
Summary
New imaging techniques like fluorescence cystoscopy improve bladder cancer detection and reduce recurrence. Further research is needed for optimal use of advanced endomicroscopic technologies in clinical practice.
Area of Science:
- Urology
- Oncology
- Medical Imaging
Background:
- Conventional white light cystoscopy requires enhancement for detecting flat and multifocal bladder lesions.
- Nonmuscle invasive bladder cancer (NMIBC) necessitates improved diagnostic tools for accurate visualization and staging.
Purpose of the Study:
- To review recent advances in imaging techniques for bladder cancer detection.
- To evaluate the efficacy of new modalities as adjuncts to conventional white light endoscopy.
Main Methods:
- Review of prospective phase III clinical trials and emerging endomicroscopic technologies.
- Comparison of fluorescence cystoscopy (using 5-aminolevulinic acid and hexaminolevulinate) and narrow band imaging with conventional methods.
Main Results:
- Fluorescence cystoscopy significantly improves detection of papillary and flat bladder lesions, leading to enhanced resection and reduced recurrence.
- Narrow band imaging offers improved visualization, particularly for carcinoma in situ, and is available in flexible and rigid formats.
- Emerging technologies like optical coherence tomography, confocal laser endomicroscopy, and Raman spectroscopy provide real-time histologic imaging.
Conclusions:
- Photodynamic diagnosis and narrow band imaging show strong evidence for clinical integration.
- Further studies are required to determine the optimal endomicroscopic technology for enhanced bladder cancer detection accuracy and clinical utility.
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