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Acral Mycosis Fungoides With Epidermal Microvesiculation Mucinosis
Erica Riveiro-Falkenbach1, Yolanda Ruano, Maria Garrido
1Departments of *Pathology, and †Dermatology, Hospital Universitario 12 de Octubre, Medical School, Universidad Complutense, Instituto de Investigación I+12, Madrid, Spain.
Abstract:
Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphoma. This entity may present with a wide spectrum of clinicopathological manifestations and mimic different dermatoses. Among its histopathological variants, spongiosis is an infrequent finding, and spongiotic microvesiculation is particularly rare. Mucinous deposition is a common event in folliculosebaceous units of folliculotropic MF but rarely described within the epidermis. Herein, we report a patient with eczematous palmoplantar lesions whereby the histological, immunohistochemical, and molecular studies confirmed to be a unique case of MF showing epidermal microvesiculation mucinosis.
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