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Updated: Apr 26, 2026

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
Published on: February 10, 2023
Mitochondrial DNA control region analysis of three ethnic groups in the Republic of Macedonia
Renata Jankova-Ajanovska1, Bettina Zimmermann2, Gabriela Huber2
1Institute of Forensic Medicine, Criminalistic and Medical Deontology, Medical Faculty, University "Ss. Cyril and Methodius", Skopje, Macedonia.
Abstract:
A total of 444 individuals representing three ethnic groups (Albanians, Turks and Romanies) in the Republic of Macedonia were sequenced in the mitochondrial control region. The mtDNA haplogroup composition differed between the three groups. Our results showed relatively high frequencies of haplogroup H12 in Albanians (8.8%) and less in Turks (3.3%), while haplogroups M5a1 and H7a1a were dominant in Romanies (13.7% and 10.3%, respectively) but rare in the former two. This highlights the importance of regional sampling for forensic mtDNA databasing purposes. These population data will be available on EMPOP under accession numbers EMP00644 (Albanians), EMP00645 (Romanies) and EMP00646 (Turks).
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