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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
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Drugs are chemical substances that modify biological responses by interacting with macromolecular targets such as receptors, ion channels, transporters, and enzymes. Pharmacodynamics describes the course of action of drugs leading to the physiological effect at a specific site in the body.
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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
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Updated: Apr 26, 2026

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
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Phytonutrients as therapeutic agents.

Charu Gupta, Dhan Prakash

    Journal of Complementary & Integrative Medicine
    |July 23, 2014
    PubMed
    Summary

    Phytonutrients, bioactive plant compounds, offer significant health benefits and therapeutic potential without side effects. This review explores their types, health roles, and market trends for disease prevention and treatment.

    Area of Science:

    • Nutritional Science
    • Pharmacology
    • Food Science

    Background:

    • Major nutrients (carbohydrates, proteins, lipids, vitamins, minerals) are essential for human health.
    • Bioactive food components, known as phytonutrients, offer additional health benefits.
    • Phytonutrients modulate immune function and can aid in disease prevention and treatment.

    Purpose of the Study:

    • To summarize the major types of phytonutrients.
    • To review their roles in promoting human health and as therapeutic agents.
    • To discuss current market trends and commercialization of phytonutrients.

    Main Methods:

    • Literature review of scientific articles on phytonutrients.
    • Categorization of phytonutrients based on their chemical structures and biological activities.

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  • Analysis of pharmacological effects and clinical applications.
  • Main Results:

    • Key phytonutrients include polyphenols, terpenoids, resveratrol, flavonoids, carotenoids, and omega-3 fatty acids.
    • These compounds exhibit diverse pharmacological effects: antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and more.
    • Phytonutrients are cost-effective, natural alternatives to conventional therapies with minimal side effects.

    Conclusions:

    • Phytonutrients are crucial for maintaining health and preventing diseases.
    • Their therapeutic potential is vast, offering a promising avenue for natural medicine.
    • Understanding phytonutrient benefits and market trends is vital for healthcare and industry professionals.