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Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...
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Articles linked to this work by shared authors, journal, and citation graph.

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Dissociation of histamine releasing activity and T-cell reactivity of allergen conjugated with synthetic polymer.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2016
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[On 100th anniversary since birthday of Andreĭ Dmitrievich Ado].

Patologicheskaia fiziologiia i eksperimental'naia terapiia·2009
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[Overcoming of a tissue barrier by allergens--a key form of predisposition to allergy].

Patologicheskaia fiziologiia i eksperimental'naia terapiia·2009
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[H1-receptors: spontaneous activity, agonism, and reversed agonism].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2008
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[Molecular basis of allergy control].

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[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].

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Related Experiment Video

Updated: Apr 26, 2026

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules
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[Evolutionary admonition: allergy].

I S Gushchin

    Patologicheskaia Fiziologiia I Eksperimental'Naia Terapiia
    |July 24, 2014
    PubMed
    Summary

    Allergy evolved as a protective immune response in complex animals, mediated by IgE antibodies and Fc(epsilon)RI. Eliminating this allergy reactivity may pose risks to future generations.

    Area of Science:

    • Immunology
    • Evolutionary Biology
    • Allergy Research

    Context:

    • Allergic reactivity is a complex phenomenon with evolutionary roots.
    • Understanding the phylogeny of allergic responses is crucial for modern medicine.
    • The high-affinity IgE receptor (Fc(epsilon)RI) plays a central role in allergic reactions.

    Purpose:

    • To explore the evolutionary development of allergic reactivity.
    • To compare IgE-Fc(epsilon)RI interactions with IgY-CHIR-AB1 interactions.
    • To investigate the biological significance of allergy as an evolutionary adaptation.

    Summary:

    • This paper examines the evolutionary origins of allergy, proposing it as a defense mechanism in highly organized animals.
    • It details the roles of IgE antibodies and the Fc(epsilon)RI in orchestrating allergen-specific inflammation.

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  • Comparative analysis of IgE-Fc(epsilon)RI and IgY-CHIR-AB1 interactions is presented.

    • Impact:

    • The study reframes allergy not as a disease, but as an essential, albeit sometimes problematic, biological response.
    • It raises critical questions about the potential long-term consequences of suppressing allergic reactivity.
    • Findings have implications for understanding immune system evolution and managing allergic conditions.