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Updated: Apr 26, 2026

Using the Overlay Assay to Qualitatively Measure Bacterial Production of and Sensitivity to Pneumococcal Bacteriocins
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Using the Overlay Assay to Qualitatively Measure Bacterial Production of and Sensitivity to Pneumococcal Bacteriocins

Published on: September 30, 2014

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Bactericidal effect of bovine lactoferrin and synthetic peptide lactoferrin chimera in Streptococcus pneumoniae and

Nidia León-Sicairos1, Uriel A Angulo-Zamudio, Jorge E Vidal

  • 1Unidad de Investigación, Facultad de Medicina, Universidad Autónoma de Sinaloa, Cedros y Sauces, Fracc. Fresnos., C.P. 80246, Culiacán, Sinaloa, Mexico, nidialeon@uas.edu.mx.

Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
|July 24, 2014
PubMed
Summary

Bovine lactoferrin (bLF) and a chimeric peptide (LFchimera) show bactericidal effects against Streptococcus pneumoniae. These agents also reduce bacterial virulence by down-regulating key genes, offering potential for new pneumococcal infection treatments.

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