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Updated: Apr 26, 2026

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High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
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Statistical analysis with dilatation for development process of human fetuses.
Kanta Naito1, Akifumi Notsu2, Jun Udagawa3
11 Department of Mathematics, Shimane University, Japan.
Statistical Methods in Medical Research
|July 24, 2014
Summary
This study introduces a mathematical theory for harmonized fetal development using dilatation, a measure of organ relationship departure from conformal mapping. This new approach provides a quantitative understanding of complex biological growth processes.
Area of Science:
- Developmental Biology
- Mathematical Biology
- Medical Imaging
Background:
- Human fetal development involves complex organogenesis with observed, yet theoretically unexplained, harmonious relationships.
- Current understanding of these harmonized developments lacks a rigorous mathematical framework.
Purpose of the Study:
- To develop a mathematical theory for harmonized fetal development using the concept of dilatation.
- To provide a quantitative measure for the departure from conformal mapping in biological systems.
Main Methods:
- Utilizing dilatation as a measure of deviation from conformal mapping.
- Developing asymptotics for dilatation based on efficient quasiconformal mapping models.
- Applying the dilatation method to analyze human fetus data.
Main Results:
- A novel mathematical framework for understanding harmonized organ development in human fetuses has been established.
- The proposed dilatation method effectively quantifies developmental relationships.
- Asymptotic behaviors of dilatation were successfully modeled using quasiconformal mapping.
Conclusions:
- Dilatation offers a powerful mathematical tool to elucidate the principles of harmonized human fetal development.
- This quantitative approach can advance our understanding of complex biological growth and organogenesis.
- The findings pave the way for further research into the mathematical underpinnings of developmental biology.

