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Related Experiment Video

Updated: Apr 26, 2026

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Deep enteroscopy with standard endoscopes using a novel through-the-scope balloon.

Vivek Kumbhari1, Andrew C Storm1, Mouen A Khashab1

  • 1Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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Summary

A new on-demand enteroscopy (ODE) device using a through-the-scope balloon demonstrated feasibility and safety for deep enteroscopy. This innovative approach achieved high diagnostic and therapeutic yields with rapid procedure times and no adverse events.

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Area of Science:

  • Gastroenterology
  • Endoscopic Procedures
  • Medical Device Innovation

Background:

  • A novel on-demand enteroscopy (ODE) device utilizes a through-the-scope balloon with a standard colonoscope.
  • This technology aims to facilitate deep enteroscopy, both anterograde and retrograde.

Purpose of the Study:

  • To evaluate the feasibility, efficacy, and safety of the ODE device.
  • To assess diagnostic and therapeutic yields of ODE procedures.

Main Methods:

  • Retrospective single-center study of 28 ODE procedures (11 anterograde, 17 retrograde).
  • Key metrics included diagnostic/therapeutic yield, technical success, procedure time, depth of maximal insertion (DMI), and adverse events.

Main Results:

  • 100% technical success rate.
  • Mean diagnostic yields: 45% (anterograde) and 59% (retrograde).
  • Mean therapeutic yields: 36% (anterograde) and 47% (retrograde).
  • No adverse events were recorded; procedure times were rapid (24-31 minutes).

Conclusions:

  • On-demand enteroscopy (ODE) is a feasible and safe method for deep enteroscopy.
  • The ODE device offers rapid procedure times and high success rates.