Musculoskeletal and cutaneous sarcoidosis: exuberant case report

Area of Science:

• Rheumatology
• Radiology
• Pathology

Background:

• Sarcoidosis is a multisystem granulomatous disease with an unknown etiology.
• Osteoarticular involvement is a rare manifestation, typically seen in chronic, multisystem cases, and is more prevalent in Black women.
• Osseous sarcoidosis presents diagnostic challenges, with reported incidence rates between 3% and 13%.

Observation:

• The characteristic radiographic findings of osseous sarcoidosis include well-defined, rounded cysts.
• Absence of periosteal reaction and peripheral sclerosis are key radiological features.
• The small bones of the hands and feet are the most commonly affected sites.

Findings:

• This case report details a rare instance of osteoarticular sarcoidosis.
• The presentation aligns with the characteristic clinical and radiological features of the condition.
• The report emphasizes the diagnostic significance of identifying bone and joint involvement in sarcoidosis.

Implications:

• Highlighting rare cases aids in understanding the spectrum of sarcoidosis manifestations.
• Recognizing characteristic radiological signs can improve diagnostic accuracy for osseous sarcoidosis.
• Increased awareness of osteoarticular involvement is vital for comprehensive patient management and treatment strategies.