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Left ventricular mass and cardiothoracic index in patients with chronic renal disease on hemodialysis
Francisco de Assis Costa1, Rui Manuel Dos Santos Póvoa1, André Falcão Pedrosa Costa2
1Universidade Federal de São Paulo.
Insights
Chest radiography can help diagnose left ventricular hypertrophy (LVH) in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). This safe imaging method aids in identifying cardiac risk in this vulnerable population.
Area of Science:
- Cardiology
- Nephrology
- Radiology
Background:
- Left ventricular hypertrophy (LVH) is a significant predictor of cardiovascular risk in patients with chronic renal disease (CRD) undergoing hemodialysis (HD).
- Early and accurate diagnosis of LVH is crucial for managing cardiovascular complications in CRD patients.
Purpose of the Study:
- To evaluate the diagnostic utility of chest radiography in identifying LVH among CRD patients on HD.
- To assess the correlation between chest radiography findings and echocardiographic measurements of LVH.
Main Methods:
- A cross-sectional study involving 100 CRD patients on HD.
- Echocardiography and chest X-rays were performed within one hour post-HD session.
- Cardiomegaly was assessed using the cardiothoracic index (CTI).
Main Results:
- LVH was detected in 83% of patients, with 67.4% showing concentric and 32.6% eccentric patterns.
- Cardiomegaly (CTI > 0.5) was present in 61% of patients.
- Chest radiography showed 66.2% sensitivity, 70.5% specificity, and 68.0% accuracy for LVH diagnosis, with a positive correlation (r=0.552) between CTI and left ventricular mass index (LVMI).
Conclusions:
- Chest radiography serves as a safe and effective diagnostic tool for LVH in CRD patients on HD.
- Radiographic findings, particularly cardiomegaly, can indicate LVH, aiding in risk stratification.
Introduction:
Left ventricular hypertrophy (LVH) is an independent predictor of cardiovascular risk in patients with chronic renal disease (CRD) on hemodialysis (HD).
Objective:
To show the usefulness of chest radiography in the diagnosis of LVH in CRD patients on HD.
Methods:
Cross-sectional study including 100 patients (58 men and 42 women), mean age 46.2 ± 14.0 years, with CRD of all causes, for at least six months on HD. Were obtained echocardiogram and chest x-rays of patients, always up to one hour after the end of HD sessions.
Results:
LVH was detected in 83 patients (83%), of whom 56 (67.4%) had the concentric pattern and 27 (32.6%) with eccentric pattern of LVH. Cardiomegaly - defined by cardiothoracic index (CTI) > 0.5 - was present in 61 patients (61%). The following were the sensitivity, specificity and accuracy, respectively, for the variable ICT: 66.2%, 70.5% and 68.0%. The Pearson correlation between ICT and index of left ventricular mass (LVMI) was 0.552 (p < 0.05) and positive likelihood ratio of 2.2.
Conclusion:
Chest radiography is a safe and useful as a diagnostic tool of LVH in CKD patients on HD.
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