Related Experiment Video
Updated: Apr 26, 2026
09:14
Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
Published on: December 30, 2025
339
[Causes and pathogenesis of hypocoagulation in reconstructive maxillofacial surgery]
Anesteziologiia I Reanimatologiia
|July 25, 2014
Summary
Reconstructive maxillofacial surgery anesthesia can cause bleeding issues due to hypocoagulation. Disseminated intravascular coagulation is the primary cause of these blood clotting disturbances in patients.
Area of Science:
- Anesthesiology
- Hematology
- Oral and Maxillofacial Surgery
Context:
- Reconstructive maxillofacial surgery often involves significant blood loss.
- Hypocoagulation, a state of reduced blood clotting ability, is a common complication.
- Potential causes include dilution coagulopathy and disseminated intravascular coagulation.
Purpose:
- To investigate the causes of hypocoagulation during anesthesia for reconstructive maxillofacial surgery.
- To analyze coagulograms and identify specific blood clotting disturbances.
Summary:
- Anesthesia for reconstructive maxillofacial surgery is associated with hypocoagulation and substantial blood loss.
- Coagulogram analysis revealed that all patients exhibited disturbances in their blood clotting system.
- Disseminated intravascular coagulation was identified as the predominant cause of hypocoagulation in this patient cohort.
Impact:
- Highlights the critical role of disseminated intravascular coagulation in anesthetic complications during maxillofacial reconstruction.
- Informs anesthetic management strategies to mitigate bleeding risks.
- Emphasizes the need for vigilant monitoring of coagulation status in these patients.
Related Concept Videos
01:20Extrinsic and Intrinsic Pathways of Hemostasis
10.8K
Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
10.8K
01:24Disorders of Hemostasis
2.7K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.7K
01:24Healing II: Complications
31
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
31
01:05Introduction to Hemostasis
13.9K
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
13.9K
01:09Coagulation
8.3K
The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
8.3K
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
2.6K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.6K