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Assessment of cervicovaginal vascular endothelial growth factor in predicting preterm delivery
Embiye Yilmaz1, Emin Ustunyurt, Sakir Kucukkomurcu
1Department of Obstetrics and Gynecology, Faculty of Medicine, Uludağ University, Bursa, Turkey.
Aim:
The aim of this study is to estimate the effectiveness of cervicovaginal vascular endothelial growth factor (VEGF) in predicting preterm delivery.
Methods:
Cervicovaginal VEGF was measured in 30 women who presented symptoms or signs of threatened preterm labor and the control group of 30 healthy pregnant patients by enzyme-linked immunoassay.
Results:
There was no statistically significant difference in cervicovaginal VEGF values between the threatened preterm labor group and the control group (P > 0.05). Similarly, no statistically significant difference was observed in terms of cervical length and cervicovaginal VEGF values between preterm and term-delivered groups (P > 0.05). Additionally, there was no correlation between cervicovaginal VEGF values and cervical length (P > 0.05) between the threatened preterm labor and the control groups.
Conclusion:
No correlation was found between cervicovaginal VEGF values and the preterm delivery. However, we believe that the role of VEGF in preterm delivery needs to be investigated further in well-designed studies with larger samples.
