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Accommodation insufficiency induced by glybenclamide
J Teller1, M Rasin, F A Abraham
1Department of Ophthalmology, Golda Medical Center, Petah-Tiqva, Israel.
Annals of Ophthalmology
|July 1, 1989
Summary
Acute accommodation insufficiency, a vision problem, can occur after taking glybenclamide. This adverse drug effect resolved after discontinuing the hypoglycemic agent.
Area of Science:
- Ophthalmology
- Pharmacology
- Endocrinology
Background:
- Glybenclamide is a common oral hypoglycemic agent used for type 2 diabetes management.
- Adverse drug reactions can manifest in various ways, impacting different organ systems.
- Ocular side effects of medications are increasingly recognized.
Observation:
- A patient developed acute accommodation insufficiency following oral glybenclamide administration.
- Accommodation insufficiency is characterized by the eye's reduced ability to change focus.
Findings:
- The case report details a previously undocumented adverse effect of glybenclamide.
- The visual symptoms resolved completely upon cessation of the hypoglycemic drug.
- This suggests a direct link between glybenclamide and the observed ocular dysfunction.
Implications:
- Highlights the potential for glybenclamide to cause acute accommodation insufficiency.
- Suggests ophthalmologists and endocrinologists should consider this side effect in patients on glybenclamide.
- Underscores the importance of thorough medication review for unexplained visual disturbances.