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Blood pressure control and exaggerated blood pressure response in nigerians with essential hypertension

Olugbenga O Abiodun1, Michael O Balogun1, Rasaaq A Adebayo1

  • 1Department of Medicine, Cardiology Unit, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Osun State, Nigeria.

Clinical Medicine Insights. Cardiology
|July 25, 2014
PubMed

Insights

Good blood pressure (BP) control is crucial for hypertensive individuals. This study found that exaggerated blood pressure response during exercise is significantly higher in those with uncontrolled BP, highlighting the importance of BP management.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Exercise Physiology

Background:

  • Effective blood pressure (BP) control is vital for reducing cardiovascular morbidity and mortality in hypertensive patients.
  • Assessing BP control during rest and exercise is crucial for comprehensive patient management.

Purpose of the Study:

  • To evaluate BP control in Nigerian hypertensive individuals at rest and during physical exertion.
  • To identify factors associated with BP control and exercise response in this population.

Main Methods:

  • Recruited 85 male hypertensive patients for clinical evaluation and treadmill (TM) exercise testing using the Bruce protocol.
  • Employed statistical analyses including independent t-test, chi-square, and Fisher's exact tests for group comparisons.
  • Utilized logistic regression and general linear models for confounder adjustment.

Main Results:

  • Controlled BP group exhibited significantly lower resting systolic BP (rSBP) and diastolic BP (rDBP) (P < 0.001).
  • The proportion of subjects with controlled BP was 37.7%.
  • Uncontrolled BP group showed significantly higher adjusted peak systolic BP (PSBP) during exercise (P = 0.001) and a higher prevalence of exaggerated blood pressure response (EBPR) (44% vs 0.1%, P = 0.003).

Conclusions:

  • Exaggerated blood pressure response (EBPR) is significantly more prevalent in hypertensive individuals with uncontrolled BP.
  • Maintaining good BP control appears to be a key factor in preventing EBPR in hypertensive patients.
  • These findings underscore the importance of consistent BP management for cardiovascular health during exercise.
Abstract

Keywords:
Nigeriansblood pressure controlexaggerated blood pressure responsehypertension

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