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Published on: April 30, 2019
The natural history of primary biliary cirrhosis
Mohamad H Imam1, Keith D Lindor2
1Department of Internal Medicine, University of North Dakota, Fargo, North Dakota.
Abstract:
Our understanding of the natural history of primary biliary cirrhosis (PBC) has been evolving especially following the introduction of ursodeoxycholic acid (UDCA). A clearer understanding of disease pathophysiology and earlier diagnosis with increased prevalence of the disease worldwide has led to increased interest and improved outcomes in patients with PBC. In this article, the authors touch briefly on features of the disease and describe the natural history of PBC prior to and after the introduction of UDCA.
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