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Updated: Apr 26, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Occlusal Classification in Relation to Original Cleft Width in Patients With Unilateral Cleft Lip and Palate
Objective:
To determine a correlation between the width of the cleft palate measured at the time of lip adhesion, definitive lip repair, and palatoplasty and the subsequent occlusal classification of patients born with unilateral cleft lip and palate.
Design:
Retrospective, observational study.
Setting:
Referral, urban, children's hospital Participants : Dental models and records of 270 patients were analyzed.
Interventions:
None.
Main Outcome Measure:
Angle occlusion classification.
Results:
The mean age at which occlusal classification was determined was 11 ± 0.3 years. Of the children studies, 84 were diagnosed with Class I or II occlusion, 67 were diagnosed with Class III occlusion, and 119 were lost to follow up or transferred care. Mean cleft widths were significantly larger in subjects with Class III occlusion for all measures at time of lip adhesion and definitive lip repair (P < .02). At time of palatoplasty, cleft widths were significantly greater at the alveolus (P = .025) but not at the midportion of the hard palate (P = .35) or posterior hard palate (P = .10).
Conclusion:
Cleft widths from the lip through to the posterior hard palate are generally greater in children who are diagnosed with Class III occlusion later in life. Notably, the alveolar cleft width is significantly greater at each time point for patients who went on to develop Class III occlusion. There were no significant differences in cleft widths between patients diagnosed later with Class I and Class II occlusions.
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