Factors influencing return-to-work after cerebrovascular disease: the importance of previous cardiovascular risk
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Updated: Apr 26, 2026

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Published on: December 29, 2023
Carlos Catalina-Romero1, Luis Miguel Ruilope2, Miguel Angel Sánchez-Chaparro3
1Ibermutuamur (Mutua de Accidentes de Trabajo y Enfermedades Profesionales de la Seguridad Social 274), Madrid, Spain carloscatalina@ibermutuamur.es.
Insights
Lower cardiovascular risk and absence of risk factors like hypertension, smoking, and diabetes are linked to higher return-to-work rates after cerebrovascular events. Managing these factors may improve rehabilitation outcomes.
Area of Science:
- Cardiology
- Neurology
- Occupational Health
Background:
- Prior cardiovascular risk (CVR) role in post-cerebrovascular event return-to-work (RTW) is under-investigated.
- Understanding CVR and risk factors is crucial for recovery and workforce reintegration.
Purpose of the Study:
- To analyze the association between prior cardiovascular risk (CVR) level, cardiovascular risk factors (CVRFs), and return-to-work (RTW) after cerebrovascular disease.
- To identify predictors of RTW in patients following a cerebrovascular event.
Main Methods:
- Prospective observational study of 348 patients from the ICARIA study cohort.
- Global CVR assessed using the SCORE system; association of demographics, work variables, CVRFs, and RTW investigated.
Main Results:
- 73.0% of patients returned to work; median loss of 12 working years due to disability.
- Low CVR level (OR: 2.55) and absence of hypertension (OR: 1.95), smoking (OR: 2.26), and diabetes (OR: 2.46) were associated with higher RTW likelihood.
Conclusions:
- Low CVR and absence of key CVRFs predict RTW rates post-cerebrovascular events.
- Controlling hypertension, smoking, and diabetes may enhance rehabilitation and secondary/tertiary prevention effectiveness.
Background:
The role of prior cardiovascular risk (CVR) in the multifactorial process of returning to work after a cerebrovascular event has not been adequately investigated. Therefore, the objective of the present study was to analyse the association between previous CVR level, cardiovascular risk factors (CVRFs) and return-to-work (RTW) following cerebrovascular disease.
Design:
This was a prospective observational study.
Methods:
We analysed a cohort of 348 patients who had experienced an episode of cerebrovascular disease-related work absence. These individuals were selected from the ICARIA study (Ibermutuamur CArdiovascular RIsk Assessment). Global CVR was assessed using the SCORE system. We investigated the association between demographics, work-related variables, CVRFs and RTW following a cerebrovascular event.
Results:
We found that a total of 254 individuals (73.0%; 95% CI: 68.3-77.7) returned to work after cerebrovascular disease. Also, we observed a median loss of 12 working years due to disability. Moreover, adjusting for potential confounders revealed that low CVR level and the absence of the following CVRFs was associated with a higher likelihood of RTW: low vs moderate-to-high CVR level (OR: 2.55; 95% CI: 1.42-4.57), no hypertension before stroke (OR: 1.95; 95% CI: 1.11-3.41), non-smoker status (OR: 2.26; 95% CI: 1.30-3.93) and no previous diabetes (OR: 2.46; 95% CI: 1.26-4.79).
Conclusions:
Low CVR, along with the absence of several CVRFs, can be used to predict RTW rates following cerebrovascular events. Therefore, controlling hypertension, tobacco consumption and diabetes might contribute to the effectiveness of multidisciplinary rehabilitation and/or secondary/tertiary prevention programs for cerebrovascular disease.
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