Related Experiment Video

Updated: Apr 26, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

14.8K

Serum lipid profile and its association with hypertension in Bangladesh

Kamrun Nahar Choudhury1, A K M Mainuddin2, Mohammad Wahiduzzaman3

  • 1Department of Epidemiology, National Centre for Control of Rheumatic Fever and Heart Disease, Bangladesh, Dhaka, Bangladesh.

Vascular Health and Risk Management
|July 26, 2014
PubMed

Insights

Hypertension in Bangladesh is closely linked to dyslipidemia, characterized by higher total cholesterol, triglycerides, and LDL, and lower HDL. Regular monitoring of blood pressure and lipid profiles is crucial for cardiovascular disease prevention.

Area of Science:

  • Cardiology
  • Public Health
  • Clinical Biochemistry

Background:

  • Hypertension and dyslipidemia are leading risk factors for cardiovascular disease (CVD) in Bangladesh.
  • These conditions contribute significantly to morbidity and mortality within the Bangladeshi population.
  • Understanding the relationship between lipid profiles and hypertension is vital for public health initiatives.

Purpose of the Study:

  • To investigate the association between serum lipid profiles and hypertension in Bangladeshi patients.
  • To compare lipid profiles of hypertensive individuals with normotensive controls.
  • To identify specific lipid abnormalities associated with hypertension in this population.

Main Methods:

  • A cross-sectional study involving 234 participants (159 hypertensive, 75 normotensive) in Dhaka, Bangladesh.
  • Data collection included sociodemographic factors, anthropometric measurements, blood pressure, and lipid profiles (TC, TG, LDL, HDL).
  • Statistical analysis, including logistic regression, was used to determine associations.

Main Results:

  • Hypertensive patients exhibited significantly higher systolic and diastolic blood pressure compared to normotensive controls.
  • Serum levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein (LDL) were significantly higher in hypertensive subjects.
  • High-density lipoprotein (HDL) levels were significantly lower in hypertensive individuals compared to normotensives.

Conclusions:

  • Hypertensive patients in Bangladesh demonstrate a strong association with dyslipidemia.
  • Regular measurement of blood pressure and lipid profiles is recommended for hypertensive individuals.
  • Early detection and management of dyslipidemia in hypertensive patients can aid in preventing CVD, stroke, and other comorbidities.
Abstract

Keywords:
Risk factorsblood pressurecardiovascular diseasesdyslipidemia

More Related Videos

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

8.4K

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
839
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
849
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
1.2K
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
989
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
5.1K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.7K