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Effect of glutaraldehyde fixation on cell surface binding capacity of Candida albicans
J Mleczko1, L L Litke, H S Larsen
1Department of Microbiology, Texas Tech University Health Sciences Center, Lubbock 79430.
Infection and Immunity
|October 1, 1989
Abstract:
The ability of viable and glutaraldehyde-fixed, stationary-phase yeast cells of Candida albicans to bind concanavalin A and monospecific antiserum for antigenic factor 1 was examined. Both fluorescence flow cytometric analysis and transmission electron microscopy indicated that glutaraldehyde-fixed cells bound less of the two reagents than did unfixed viable cells.