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Related Concept Videos

Gallbladder01:17

Gallbladder

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The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
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Cholecystitis01:20

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Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
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Appendicitis01:19

Appendicitis

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Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
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Diseases of the Liver and Gallbladder01:26

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Appendicitis-I: Introduction01:22

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

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Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
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Determining Bile Duct Density in the Mouse Liver
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Acalculous diffuse gallbladder wall thickening in children.

Ji Haeng Lee1, Young Eun No2, Yeoun Joo Lee2

  • 1Postgraduate School of Medicine, Pusan National University, Yangsan, Korea.

Pediatric Gastroenterology, Hepatology & Nutrition
|July 26, 2014
PubMed
Summary
This summary is machine-generated.

Acalculous gallbladder wall thickening in children is often caused by systemic infections or diseases, not intrinsic gallbladder issues. Treatment of the underlying condition typically resolves the thickening, making surgery unnecessary unless cholecystitis is evident.

Keywords:
Acalculous cholecystitisChildGallbladder wall thickening

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Area of Science:

  • Pediatric Gastroenterology
  • Diagnostic Imaging
  • Internal Medicine

Background:

  • Gallbladder (GB) wall thickening can occur due to various conditions beyond intrinsic GB disease.
  • Understanding the causes and outcomes of acalculous GB wall thickening in children is crucial for appropriate management.

Purpose of the Study:

  • To investigate the predisposing etiologies of acalculous gallbladder wall thickening in pediatric patients.
  • To determine the clinical outcomes associated with acalculous GB wall thickening in children.

Main Methods:

  • Retrospective analysis of 67 children with acalculous GB wall thickening (GB wall diameter >3.5 mm).
  • Evaluation of underlying diseases, treatments administered, and patient outcomes.
  • Data collected from June 2010 to June 2013.

Main Results:

  • Systemic infections (35.8%) and acute hepatitis (26.9%) were the most common causes.
  • Bacterial infections were the leading cause of systemic infections.
  • Most patients (91.0%) improved with symptomatic or underlying disease treatment; 7.5% died from their primary conditions.

Conclusions:

  • Extracholecystic conditions frequently lead to diffuse GB wall thickening in children.
  • GB wall thickening often resolves with treatment of the underlying cause.
  • Avoid surgical intervention (cholecystectomy) unless clear signs of cholecystitis are present.