Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Harnessing Membrane-Active Peptides for Selective Cancer Targeting: Phosphatidylserine Recognition by Tilapia Piscidin 4.

JACS Au·2026
Same author

Logarithmic Binding and Stretched-Exponential Kinetics in Peripheral Protein Interactions with Lipid Membrane Surfaces.

The journal of physical chemistry letters·2026
Same author

AI-driven antimicrobial peptide characterization unveils novel motifs for drug design.

Scientific reports·2025
Same author

Poly-Arginine Tails and Helical Segments of Natural Antimicrobial Peptides Display Concerted Action at Membranes for Enhanced Antimicrobial Effects.

ACS bio & med chem Au·2025
Same author

Global and local effects in lipid-mediated interactions between peripheral and integral membrane proteins.

Frontiers in molecular biosciences·2025
Same author

<i>AutoRefl</i>: active learning in neutron reflectometry for fast data acquisition.

Journal of applied crystallography·2025

Related Experiment Video

Updated: Apr 26, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

16.3K

Superheating and homogeneous single bubble nucleation in a solid-state nanopore.

Gaku Nagashima1, Edlyn V Levine1, David P Hoogerheide2

  • 1School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.

Physical Review Letters
|July 26, 2014
PubMed
Summary

Researchers achieved extreme superheating and bubble nucleation in electrolyte solutions using nanopores. This method offers a new way to study metastable states of matter.

More Related Videos

Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.1K
Studying the Effects of Temperature on the Nucleation and Growth of Nanoparticles by Liquid-Cell Transmission Electron Microscopy
07:02

Studying the Effects of Temperature on the Nucleation and Growth of Nanoparticles by Liquid-Cell Transmission Electron Microscopy

Published on: February 17, 2021

5.6K

Related Experiment Videos

Last Updated: Apr 26, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

16.3K
Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.1K
Studying the Effects of Temperature on the Nucleation and Growth of Nanoparticles by Liquid-Cell Transmission Electron Microscopy
07:02

Studying the Effects of Temperature on the Nucleation and Growth of Nanoparticles by Liquid-Cell Transmission Electron Microscopy

Published on: February 17, 2021

5.6K

Area of Science:

  • Physical Chemistry
  • Nanotechnology
  • Materials Science

Background:

  • Studying metastable states of matter is crucial for understanding various physical phenomena.
  • Nanopore technology offers unique environments for investigating matter at the nanoscale.

Purpose of the Study:

  • To demonstrate extreme superheating and single bubble nucleation in an electrolyte solution within a nanopore.
  • To explore the potential of nanopore-based methods for studying metastable states.

Main Methods:

  • Utilizing Joule heating from a focused ionic current through a silicon nitride nanopore.
  • Employing modest voltage biases to induce ionic current.
  • Monitoring conductance, nucleation, and bubble evolution electronically and optically.

Main Results:

  • Achieved temperatures near the thermodynamic limit of superheat before bubble nucleation.
  • Observed homogeneous and highly reproducible bubble nucleation.
  • Demonstrated the ability to induce and monitor extreme superheating events.

Conclusions:

  • Nanopore-based Joule heating is an effective method for achieving extreme superheating.
  • The observed bubble nucleation is homogeneous and reproducible.
  • This approach has broad applications for exciting, detecting, and characterizing highly metastable states of matter.