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Updated: Apr 26, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Spindle cell sarcoma of the vulva with myofibroblastic differentiation
Amanda J Adeleye1, Nicholas Palmeri, Shih-Hsiu J Wang
1Departments of 1Obstetrics and Gynecology and 2Pathology, and 3Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, NY.
Objective:
Primary vulvar sarcomas are rare lesions of the lower genital tract. We report the case of a patient with a spindle cell sarcoma of the vulva.
Materials And Methods:
A 44-year-old woman presented with a painless vulvar mass. Vulvar biopsy demonstrated a spindle cell sarcoma with myofibroblastic differentiation.
Results:
Pretreatment evaluation revealed no evidence of metastatic disease, and magnetic resonance imaging found no local masses. The patient underwent right radical vulvectomy with negative margins and tolerated the procedure well.
Conclusions:
Women undergoing gynecologic care should have routine evaluation of the vulva to detect these rare neoplasms.
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