Seizure induced disruption of blood-brain barrier demonstrated by CT

Computed tomography of the head performed soon after a generalized seizure demonstrated diffuse bilateral contrast enhancement. The patient had undergone visceral angiography for lower extremity ischemia, and a generalized seizure was observed 90 min afterward. Postictal CT, completed without additional contrast medium administration, demonstrated diffuse patchy contrast enhancement of both cerebral and cerebellar hemispheres. The mechanism of seizure induced contrast enhancement on CT is discussed.