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Updated: Apr 26, 2026

Homing of Hematopoietic Cells to the Bone Marrow
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Homing and migration assays of hematopoietic stem/progenitor cells

Xi C He1, Zhenrui Li, Rio Sugimura

  • 1Stowers Institute for Medical Research, Kansas City, MO, USA.

Methods in Molecular Biology (Clifton, N.J.)
|July 27, 2014
PubMed

Hematopoietic stem and progenitor cells (HSPCs) reside mainly in bone marrow; however, under homeostatic and stressed conditions, HSPCs dynamically change their location-either egressing from bone marrow and getting into circulation, a process of mobilization; or coming back to the bone marrow, the homing process. How to analyze these two processes will be critical for understanding the behavior of HSPCs. Here we provide an experimental protocol to monitor and analyze homing and migration of HSPCs.

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