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Updated: Apr 26, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Treatment-related dysgeusia in head and neck cancer patients
Ekpemi Irune1, Raghav C Dwivedi1, Christopher M Nutting2
1Head & Neck Research Unit, Royal Marsden Hospital, 3rd Floor, Mulberry House, London SW3 6JJ, UK.
Abstract:
Head and neck cancer patients treated with radiotherapy and/or chemotherapy agents may develop altered taste acuity. This, together with radiation induced xerostomia and dysphagia, is a major contributory factor to the anorexia and concomitant morbidity often seen in this group of patients. This paper examines the existing literature in order to assess the prevalence of clinician and patient-reported dysgeusia in HNC patients undergoing oncological treatment. We also describe the temporal manifestations of the same and its reported impact on QOL.
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