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Updated: Apr 26, 2026

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
Published on: May 26, 2023
Antimicrobial activity of cobalt imidazolate metal-organic frameworks
Sonia Aguado1, Jennifer Quirós1, Jerome Canivet2
1Department of Chemical Engineering, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.
Abstract:
Two cobalt imidazolate metal-organic frameworks were evaluated as a bactericidal material against the growth of the Gram-negative bacteria Pseudomonas putida and Escherichia coli. Under the most unfavourable conditions, within the exponential growth phase and in the culture media for both microorganisms, the growth inhibition reached over 50% for concentrations of biocidal material in the 5-10mgL(-1) range. The release of metal gives excellent durability with the antibacterial effect persisting after 3months. Both cobalt-based materials can be prepared with simple, cheap and easily accessible commercial ligands, leading to a more affordable possible future application as antimicrobial materials.
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