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Published on: August 18, 2016
Coronary vasospasm during CT angiography
Takehiro Nakahara1, Takuji Toyama2, Yoshito Tsushima3
1Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma 371-8511, Japan.
Insights
Vasospastic angina can be challenging to diagnose, even with cardiac CT. Beta-blockers, while common for CT, may mask symptoms of this condition in susceptible patients.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Coronary artery disease diagnosis often involves cardiac CT.
- Beta-blockers are frequently administered during cardiac CT procedures.
- Vasospastic angina is a condition characterized by reversible coronary artery spasms.
Observation:
- A 71-year-old male smoker presented with post-dinner chest oppression.
- Cardiac CT with beta-blocker revealed coronary stenosis, but adenosine triphosphate-stress perfusion SPECT showed no ischemia.
- Holter monitoring later detected ST elevation during symptomatic episodes while smoking.
Findings:
- The patient was diagnosed with vasospastic angina.
- Cardiac CT performed without a beta-blocker showed non-obstructive, diffuse plaque and negative remodeling.
- Asian populations exhibit a higher prevalence of vasospastic angina.
Implications:
- Routine beta-blocker use in cardiac CT may obscure the diagnosis of vasospastic angina.
- Careful consideration of patient history and potential vasospastic angina is crucial.
- Alternative diagnostic strategies may be necessary for patients at risk for vasospastic angina.
Abstract:
A 71-year-old man, a heavy smoker, was admitted for evaluation of "chest oppression" after every dinner. Cardiac CT with a beta-blocker showed coronary stenosis in the left circumflex. Although adenosine triphosphate-stress perfusion single-photon emission CT revealed no ischemia, Holter electrocardiography belatedly indicated an ST elevation associated with his symptoms while smoking. He was diagnosed to have vasospastic angina. Cardiac CT without a beta-blocker showed thin diffuse plaque and negative remolding without any significant stenosis at the same site. Asian patients have a tendency to develop vasospastic angina. Although beta-blockers are recommended for cardiac CT, the routine administration of beta-blockers in cardiac CT may have some risk for such cases.
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