Related Experiment Video

Updated: Apr 26, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

2.8K

The association between ICD interventions and mortality is independent of their modality: clinical implications

Gianluigi Bencardino1, Antonio Di Monaco, Teresa Rio

  • 1Department of Cardiovascular Medicine, Catholic University of the Sacred Heart, Rome, Italy.

Journal of Cardiovascular Electrophysiology
|July 29, 2014
PubMed

Insights

Patients receiving implantable cardioverter-defibrillator (ICD) therapies, including antitachycardia pacing (ATP) or shocks, face increased mortality. The risk appears linked to the underlying arrhythmias, not the specific ICD therapy used.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Severe structural heart disease patients have higher mortality post-implantable cardioverter-defibrillator (ICD) shocks.
  • The impact of non-shock ICD therapies, like antitachycardia pacing (ATP), on mortality is not well understood.

Purpose of the Study:

  • To investigate the long-term mortality impact of different ICD therapies (no intervention, ATP, shocks).

Main Methods:

  • 573 patients undergoing ICD implantation were categorized into three groups: no device intervention, ATP intervention, or shock intervention.
  • All-cause mortality was the primary endpoint, analyzed over a median follow-up of 48 months.

Main Results:

  • Patients receiving ATP (43%) or shock (38%) interventions had higher mortality than those with no interventions (21%).
  • Both ATP and shock interventions were independent predictors of all-cause mortality.
  • No significant mortality difference was observed between ATP and shock intervention groups.

Conclusions:

  • Appropriate ICD interventions, whether ATP or shocks, are associated with increased mortality risk.
  • The risk appears related to the presence of sustained ventricular arrhythmias rather than the specific therapy modality.
  • These findings highlight the prognostic significance of ventricular arrhythmias in patients with ICDs.
Abstract

Keywords:
ICD shockantitachycardia pacingheart failureimplantable cardioverter-defibrillatormortalityventricular arrhythmias

More Related Videos

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation16:40

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

27.5K
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.2K

Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
746
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
786
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
1.7K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
630
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
888
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
621