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Rubella and pregnancy: diagnosis, management and outcomes

Elise Bouthry1, Olivier Picone, Ghada Hamdi

  • 1Paris-Sud University, AP-HP, Hôpital Paul Brousse, Laboratoire de Virologie, National Reference Laboratory for Maternofetal Rubella Infections, Univ Paris-Sud, UMR-S 785, INSERM U785, Villejuif, France.

Prenatal Diagnosis
|July 29, 2014
PubMed

Insights

Rubella infection in pregnancy can cause congenital rubella syndrome. This review covers the implications and management of rubella during pregnancy, despite available vaccines.

Area of Science:

  • Virology
  • Immunology
  • Obstetrics

Background:

  • Rubella is a common childhood viral illness.
  • Congenital rubella syndrome (CRS) results from maternal rubella infection during pregnancy, leading to cataracts, cardiac defects, and deafness.
  • Effective rubella vaccines exist, with vaccination programs implemented globally.

Purpose of the Study:

  • To review the implications of rubella infection during pregnancy.
  • To discuss the management strategies for rubella in pregnant individuals.
  • To highlight ongoing challenges in rubella prevention and diagnosis.

Main Methods:

  • Literature review of rubella infection in pregnancy.
  • Analysis of congenital rubella syndrome risks and outcomes.
  • Examination of current vaccination strategies and diagnostic challenges.

Main Results:

  • Rubella vaccination has significantly reduced disease incidence.
  • Congenital rubella syndrome remains a concern in unvaccinated populations or during vaccine failures.
  • Effective management and prevention strategies are crucial.

Conclusions:

  • Rubella prevention through vaccination is critical for pregnant women and their offspring.
  • Timely diagnosis and management are essential to mitigate CRS.
  • Continued efforts in public health are needed to address persistent challenges in rubella control.

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