[Histologic study of a bovine lymph node before and after antigenic stimulation. 1. Histology, cytology and...

The effect of antigenic stimulation on a bovine lymph node was studied using conventional histological and cytological techniques. The lesions observed in the bovine lymph node following immunological stimulation are similar to those described in other mammalian species. Histometrical studies showed an increase in the size of the nucleus of lymphoid cells in the stimulated lymph nodes. This probably reflects an activation of the lymphoid cell population. The number of the various cell types in the germinal centers appeared to be positively correlated with the stimulation intensity. The complete identification of the different sub-lines of lymphoid cells requires complementary immunocytochemical and electron-microscopic studies.