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Updated: Apr 26, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Foundation of evidence-based decision making for health care managers-part II: meta-analysis and applying the
1Author Affiliation: Health Services and Information Management, East Carolina University, Greenville, North Carolina.
Abstract:
This article is a continuation of a 2-part series that seeks to build the skills of health care managers and supervisors in critically reading and interpreting systematic reviews and meta-analyses. The first article, part I, defined the types of systematic reviews and outlined the process of conducting them. This article, part II, focuses on meta-analysis, a type of systematic review. This article explains the additional procedures associated with meta-analyses and describes the potential shortcomings of both systematic reviews and meta-analyses. Finally, this article provides a way for health care managers and supervisors to appraise systematic reviews and meta-analyses and to determine whether the evidence applies to their problems and settings.
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