Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ribosome Profiling02:24

Ribosome Profiling

3.2K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The landscape of CAR T-cell therapy in the United States and China: A comparative analysis.

International journal of cancer·2018
Same author

A Novel Tb@Sr-MOF as Self-Calibrating Luminescent Sensor for Nutritional Antioxidant.

Nanomaterials (Basel, Switzerland)·2018
Same author

Association of human leukocyte antigen alleles and supertypes with immunogenicity of oral rotavirus vaccine given to infants in China.

Medicine·2018
Same author

ANXC7 Is a Mitochondrion-Localized Annexin Involved in Controlling Conidium Development and Oxidative Resistance in the Thermophilic Fungus <i>Thermomyces lanuginosus</i>.

Frontiers in microbiology·2018
Same author

High mobility group box-1 induces pro-inflammatory signaling in human nucleus pulposus cells via toll-like receptor 4-dependent pathway.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2018
Same author

Molecular investigation of "Candidatus Mycoplasma haemobos" in goats and sheep in central China.

Transboundary and emerging diseases·2018

Related Experiment Video

Updated: Apr 26, 2026

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

7.4K

Biomarker studies in multiple sclerosis: from proteins to noncoding RNAs.

Xiao-Fang Liu1, Yue-Bei Luo, Zhao-Hui Luo

  • 1Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China.

Neurochemical Research
|July 30, 2014
PubMed
Summary

Biomarker research in multiple sclerosis (MS) aids early diagnosis and treatment monitoring. This review covers recent advances in protein and noncoding RNA biomarkers for MS management.

More Related Videos

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

1.4K
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K

Related Experiment Videos

Last Updated: Apr 26, 2026

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

7.4K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

1.4K
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K

Area of Science:

  • Neuroimmunology
  • Biomarker Discovery

Background:

  • Multiple sclerosis (MS) is a complex neuroimmunological disorder.
  • Demyelination and axonal injury characterize MS pathophysiology.
  • Early diagnosis and personalized treatment of MS remain challenging.

Purpose of the Study:

  • To review recent developments in biomarker studies for multiple sclerosis.
  • To highlight the role of biomarkers in MS prediction, diagnosis, and management.
  • To cover biomarkers ranging from proteins to noncoding RNAs.

Main Methods:

  • Literature review of recent biomarker studies in MS.
  • Focus on protein molecules and noncoding RNAs as potential biomarkers.
  • Synthesis of current understanding of MS biomarker applications.

Main Results:

  • Biomarkers are crucial for early MS prediction and diagnosis.
  • Biomarkers assist in monitoring disease activity.
  • Biomarkers help predict patient response to therapies.

Conclusions:

  • Advancements in biomarker research offer improved strategies for MS.
  • Protein and noncoding RNA biomarkers show promise for clinical application.
  • Biomarkers are essential for individualized MS management.