Tissue dissolution by a novel multisonic ultracleaning system and sodium hypochlorite

Area of Science:

• Endodontics
• Biomaterials Science
• Biomedical Engineering

Background:

• Evaluating novel endodontic irrigation systems is crucial for improving clinical outcomes.
• Conventional irrigation methods face challenges in effectively removing tissue debris.
• The Multisonic Ultracleaning System presents a new approach to endodontic cleaning.

Purpose of the Study:

• To compare the tissue dissolution efficacy of the Multisonic Ultracleaning System against established endodontic irrigation devices.
• To quantify the rate of tissue dissolution achieved by different irrigation systems under varying conditions.
• To assess the impact of sodium hypochlorite concentration and temperature on tissue dissolution.

Main Methods:

• Bovine muscle tissue was subjected to irrigation by four devices: Multisonic Ultracleaning System, Piezon Master 700, EndoVac, and a conventional needle.
• Irrigation was performed using 0.5%, 3%, and 6% sodium hypochlorite (NaOCl) solutions at 21°C and 40°C.
• Tissue mass change and dissolution time were measured to calculate the rate of tissue dissolution (%/s).

Main Results:

• The Multisonic Ultracleaning System demonstrated the highest rate of tissue dissolution across all tested NaOCl concentrations.
• Tissue dissolution rates increased with higher NaOCl concentrations and temperatures for all devices.
• The Multisonic Ultracleaning System's dissolution rate was over 8 times faster than the next most effective device tested.

Conclusions:

• The Multisonic Ultracleaning System significantly outperforms conventional irrigation devices in terms of in vitro tissue dissolution.
• This novel system shows potential for enhanced cleaning efficacy in endodontic treatments.
• Optimizing NaOCl concentration and temperature further improves tissue dissolution rates.