Pericoronary pseudotumor caused by helicobacter cinaedi

Tatsuichiro Seto1, Tamaki Takano, Hajime Ichimura

  • 1Department of Surgery, Shinshu University School of Medicine.

Insights

A rare pericoronary lesion caused by Helicobacter cinaedi infection was successfully treated with ceftriaxone. This case highlights the importance of considering infectious causes for cardiac tumors and tumor-like lesions.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Radiology

Background:

  • Cardiac tumors are rare, with most being true neoplasms.
  • Pericoronary lesions are uncommon and can mimic neoplasms.

Observation:

  • A 39-year-old man presented with fever and chest pain, later found to have a pericoronary lesion.
  • Initial antibiotic treatment with clarithromycin was ineffective.
  • Helicobacter cinaedi (H. cinaedi) was identified in blood cultures.

Findings:

  • Computed tomography (CT) revealed a lesion around the right coronary artery with no (18)F-fluorodeoxyglucose uptake.
  • Ceftriaxone treatment led to a significant reduction in lesion size on serial CT scans.
  • The lesion was attributed to H. cinaedi infection.

Implications:

  • This case suggests H. cinaedi infection as a potential cause of cardiac tumor-like lesions.
  • Infectious etiologies should be considered in the differential diagnosis of pericoronary masses.
  • Successful antibiotic treatment of such lesions is feasible.

Related Concept Videos

Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
43
Peptic Ulcer01:27

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
46
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
1.2K
Peptic Ulcer Disease I: Introduction01:25

Peptic Ulcer Disease I: Introduction

Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
24
Peptic Ulcer Disease II: Pathophysiology01:24

Peptic Ulcer Disease II: Pathophysiology

Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
40
Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
3.0K