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Fiber-assisted molding (FAM) of surfaces with tunable curvature to guide cell alignment and complex tissue
Vahid Hosseini1, Philip Kollmannsberger, Samad Ahadian
1Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, CH-8093, Zurich, Switzerland.
Small (Weinheim an Der Bergstrasse, Germany)
|July 30, 2014
Abstract:
A simple and robust method termed "fiber-assisted molding (FAM)" is presented to create biomimetic three-dimensional surfaces with controllable curvature and helical twist. The alignment of muscle fibrils and the assembly of helically patterned extracellular matrix by cells demonstrate the potential of this method for tissue engineering and other materials science applications.
