Inflammatory nevus comedonicus with epidermoid cyst

Area of Science:

• Dermatology
• Medical Case Reports
• Genetics

Background:

• Nevus comedonicus (NC) is a rare congenital adnexal hamartoma.
• It typically presents as multiple comedones in a grouped or linear pattern.
• Inflammatory variants and associations with other conditions are infrequently reported.

Purpose of the Study:

• To report a unique case of inflammatory nevus comedonicus.
• To highlight the isolated involvement of the lower limb along Blaschko's lines.
• To document the rare co-occurrence with epidermoid cysts.

Main Methods:

• Clinical presentation and dermatoscopic examination.
• Histopathological analysis of skin biopsy.
• Review of relevant literature.

Main Results:

• A young male presented with inflammatory lesions resembling comedones along Blaschko's lines on the right lower limb.
• Histopathology confirmed nevus comedonicus.
• Associated epidermoid cysts were identified, a rare finding in this context.
• The distribution was exclusively limited to the lower limb.

Conclusions:

• This case underscores the variable presentation of nevus comedonicus.
• Isolated lower limb involvement along Blaschko's lines is a rare manifestation.
• The association with epidermoid cysts warrants further investigation and recognition.