Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Identifying Suicidality Risk in Adolescent Gynecology: Implications of Combined PHQ-2 and ASQ Screening.

Journal of pediatric and adolescent gynecology·2026

Same author

Daily Symptom Home Monitoring Decreases Hospital Readmissions in Children and Young Adults With Acute Lymphoblastic Leukemia.

Cancer medicine·2026

Same author

Optimal designs for discrete-time survival models with competing risks.

Lifetime data analysis·2026

Same author

Two-level non-regular fractional factorial designs for public health studies.

BMC medical research methodology·2026

Same author

Minimax optimal designs via particle swarm optimization methods.

Statistics and computing·2025

Same author

Influence of Surgical Technique and Surgical Skill on Outcomes of Cleft Palate Repair.

Plastic and reconstructive surgery·2025

Search research articles

Related Experiment Video

Updated: Apr 26, 2026

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

Recent developments in optimal experimental designs for functional magnetic resonance imaging.

Ming-Hung Kao¹, M'hamed Temkit¹, Weng Kee Wong¹

¹Ming-Hung Kao, M'hamed Temkit, School of Mathematical and Statistical Sciences, Arizona State University, Tempe, AZ 85287, United States.

World Journal of Radiology

|July 30, 2014

Summary

This paper surveys recent advances in experimental designs for functional magnetic resonance imaging (fMRI) studies. It highlights new Hadamard matrix-based designs that offer statistically optimal brain mapping for precise inference of brain functions.

Keywords:

A-optimality Blocked designs D-optimality Design efficiencies Genetic algorithms Hadamard sequences M-sequences

More Related Videos

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

Related Experiment Videos

Last Updated: Apr 26, 2026

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Published on: September 22, 2014

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

Area of Science:

Neuroimaging
Cognitive Neuroscience
Brain Mapping

Background:

Functional magnetic resonance imaging (fMRI) is a key technology for studying brain activity.
High-quality experimental designs are crucial for accurate inference in fMRI studies.
Existing designs like blocked designs and m-sequences have limitations.

Purpose of the Study:

To provide a comprehensive survey of recent developments in fMRI experimental designs.
To introduce analytical and computational tools for optimizing fMRI designs.
To present novel Hadamard matrix-based designs for fMRI.

Main Methods:

Literature review of recent fMRI design developments.
Discussion of analytical and computational tools for design optimization.
Presentation and theoretical analysis of Hadamard matrix-based fMRI designs.

Main Results:

Hadamard matrix-based designs demonstrate potential for statistically optimal fMRI experiments.
These new designs can enhance the precision and validity of brain function inference.
The survey covers commonly used designs and introduces cutting-edge approaches.

Conclusions:

Recent advancements in fMRI experimental design are critical for neuroimaging research.
Hadamard matrix designs represent a promising direction for optimizing fMRI data collection.
Further research into fMRI design methodologies is essential for advancing brain mapping.