Related Experiment Video
Updated: Apr 26, 2026
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Braided pattern in a dermatofibrosarcoma protuberans: a potential mimicker of neural neoplasms
Angel Santos-Briz1, Erica Riveiro-Falkenbach, Concepción Román-Curto
1*Department of Pathology, Hospital Universitario de Salamanca, Salamanca, Spain; †Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain; ‡Department of Pathology, Hospital Universitario 12 de Octubre, Instituto de Investigación I+12, Madrid, Spain; §Service of Dermatology, Hospital Universitario de Salamanca, Salamanca, Spain; ¶Molecular Cytogenetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre-CNIO, Madrid, Spain; and ‖Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany.
Abstract:
Dermatofibrosarcoma protuberans (DFSP) is a dermal and subcutaneous slow-growing tumor of intermediate malignancy. Different histological variants of DFSP have been described, depending on cellular and stromal peculiarities. Here, we report the histological features of a DFSP in which cells were frequently arrayed in cords and fascicles that were interweaved, conforming a peculiar braided pattern. This finding might pose difficulties in the differential diagnosis with neural neoplasms and expands the morphological spectrum of DFSP.
