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Updated: Apr 26, 2026

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Large left ventricular metastasis in patient with liposarcoma
Gregory Dendramis1, Daniela Di Lisi, Claudia Paleologo
1U.O.C. di Cardiologia, Scuola di Specializzazione in Malattie dell'Apparato Cardiovascolare, A.O.U.P. 'P. Giaccone', Università degli Studi di Palermo, Palermo, Italy.
Metastases to the heart are rare. This case highlights a large, mobile cardiac mass found in a patient with advanced dedifferentiated liposarcoma, detected via echocardiogram.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac metastases are uncommon, posing diagnostic challenges.
- Dedifferentiated liposarcoma is a rare soft tissue sarcoma.
Observation:
- A 44-year-old male with pleural dedifferentiated liposarcoma presented with advanced disease.
- Transthoracic echocardiography revealed a large, mobile, lobulated cardiac mass.
Findings:
- The mass was attached to the left ventricle's basal posterior wall with intracavitary growth.
- The tumor extended to the inferolateral and inferoseptal walls of the left ventricle.
Implications:
- This case underscores the importance of considering cardiac involvement in advanced sarcomas.
- Echocardiography is crucial for diagnosing and characterizing cardiac masses.
- Understanding rare metastatic patterns aids in comprehensive patient management.
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