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Updated: Apr 26, 2026
04:45
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
4.6K
Matter of margins.
Summary
Surgical excision of basal cell carcinoma (BCC) had a 4.97% incomplete removal rate. Factors like ulceration and tumor type influence margin involvement, impacting recurrence risk.
Area of Science:
- Dermatology
- Surgical Oncology
- Cancer Research
Background:
- Basal cell carcinoma (BCC) is the most common cancer, posing a significant economic burden.
- Surgical excision with margin assessment is the standard treatment for BCC.
- Incomplete tumor removal is a poor prognostic indicator, increasing the risk of local recurrence.
Purpose of the Study:
- To conduct a retrospective analysis of surgical activity for BCC.
- To evaluate therapeutic accuracy in BCC removal.
- To identify prognostic factors associated with incomplete BCC excisions.
Main Methods:
- Retrospective review of 4523 BCC removals.
- Exclusion of other neoplasms, benign lesions, and biopsies.
- Assessment of BCC size, diameter, localization, histology, and complicating factors.
Main Results:
- Incomplete BCC resections occurred in 4.97% of cases.
- Ulceration was the most frequent complicating factor (22.9%).
- Histological subtypes and specific factors like actinic keratoses and perineural invasion influenced margin involvement.
Conclusions:
- The study identified key factors contributing to incomplete BCC excisions.
- Understanding these factors can improve surgical planning and reduce recurrence rates.
- Dermatologists' case series, though smaller, show higher efficacy in complete surgical excision.
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