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Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography
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Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography

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Phasing tiny crystals

Jianwei Miao1, Jose A Rodriguez2

  • 1Department of Physics and Astronomy, and California NanoSystems Institute, University of California , Los Angeles, CA 90095, USA.

Iucrj
|July 31, 2014
PubMed

Abstract:

For tiny crystals, their diffraction intensities at and between the Bragg peaks become measurable due to the limited number of the unit cells, which can in principle be used to directly phase the crystal structures.

Keywords:
X-ray free electron laserscoherent diffraction imagingoversamplingphase retrieval

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