Elbow synovium as the initial site of colon adenocarcinoma metastasis: diagnosis by arthroscopic biopsy

An acutely painful and swollen isolated joint has a broad differential. We present the case of an elderly male with four-month progressive, painful swelling of the right elbow. After an initial workup for inflammatory arthropathies was nondiagnostic and a trial of conservative management failed to relieve his pain, a diagnostic arthroscopy was performed. Biopsy revealed metastatic colon adenocarcinoma isolated to the synovial tissue of the elbow. This case provides an example of the presentation and progression of synovial metastasis from a visceral cancer and can potentially guide physicians in the diagnosis and management of similar cases.