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Related Concept Videos

Nose and Nasal Cavity01:24

Nose and Nasal Cavity

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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
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Updated: Apr 26, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Sinonasal malignancy: presentation and outcomes.

Y B Mahalingappa1, H S Khalil1

  • 1ENT Department,Plymouth Hospitals NHS Trust,UK.

The Journal of Laryngology and Otology
|July 31, 2014
PubMed
Summary
This summary is machine-generated.

Late-stage diagnosis of sinonasal malignancy leads to higher mortality. This study highlights the need for improved early detection and treatment strategies for these rare head and neck cancers.

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Area of Science:

  • Otolaryngology
  • Head and Neck Surgery
  • Oncology

Background:

  • Sinonasal malignancy is rare, often presenting at advanced stages.
  • Effective management requires adherence to established guidelines.

Purpose of the Study:

  • To analyze presentation, diagnosis, and treatment outcomes of sinonasal malignancy.
  • To compare findings with the European Position Paper on Endoscopic Management.

Main Methods:

  • Retrospective audit of sinonasal malignancy patients over five years.
  • Review of clinical records and imaging data.

Main Results:

  • 30 cases identified; nasal cavity and maxillary sinuses most common sites.
  • Squamous cell carcinoma (50%) and malignant melanoma (27%) were prevalent.
  • High incidence of late-stage (III/IV) presentation (70%); 30% mortality rate.
  • Endoscopic surgery utilized in only 20% of cases.

Conclusions:

  • Late-stage presentation significantly increases patient mortality.
  • High rates of malignant melanoma observed, with notable recurrence and survival challenges.