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Updated: Apr 26, 2026
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Relationship between foveal microstructures and visual outcomes in eyes with resolved central serous
Taiji Hasegawa1, Masahiro Okamoto, Naonori Masuda
1Department of Ophthalmology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan, taijiha@naramed-u.ac.jp.
Purpose:
To determine whether significant correlations exist between the foveal microstructures and visual outcomes in eyes with resolved central serous chorioretinopathy (CSC).
Methods:
We retrospectively reviewed the medical records of patients who had a complete resolution of the serous retinal detachment (SRD) and had an intact ellipsoid zone in the fovea in the spectral-domain optical coherence tomographic (SD-OCT) images. Twenty-five eyes with CSC (CSC group) and 18 unaffected fellow eyes (control group) of 23 patients were evaluated. The eyes in the CSC group were divided into those with (n = 11) and those without (n = 14) visual disturbances after resolution of the SRD. The thickness of each retinal layer at the fovea was measured in the SD-OCT images.
Results:
The photoreceptor outer segment (OS) length in the CSC group was significantly shorter than that in the control group (p = 0.0003). In addition, the photoreceptor OS length in the visual disturbances group was significantly shorter and the duration of SRD was significantly longer than that in the no visual disturbances group (p = 0.0230, p = 0.0021, respectively).
Conclusions:
The photoreceptor OS length is a good parameter to indicate the integrity of the foveal photoreceptors in eyes with a resolved CSC.
