Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Long-term follow-up of a Coxiellosis outbreak in a goat flock].

Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·2026
Same author

Optimization of a bovine whole-blood cytokine recall assay for the detection of interferon-gamma and interleukin 10 following stimulation with <i>Coxiella burnetii</i> antigens.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025
Same author

Susceptibility, Immunity, and Persistent Infection Drive Endemic Cycles of Coxiellosis on Dairy Farms.

Animals : an open access journal from MDPI·2024
Same author

How can current oncological datasets be adjusted to support the automated patient recruitment in clinical trials?

Health informatics journal·2024
Same author

The immune response to a Coxiella burnetii vaccine in sheep varies according to their natural pre-exposure.

Vaccine·2024
Same author

Antibodies against SARS-CoV-2 Suggestive of Single Events of Spillover to Cattle, Germany.

Emerging infectious diseases·2022

Related Experiment Video

Updated: Apr 26, 2026

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses
05:49

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses

Published on: November 21, 2023

2.6K

[The PRRSV-serumneutralization test detects gaps in herd immunity].

Jens Böttcher, Michaela Alex, Britta Janowetz

    Berliner Und Munchener Tierarztliche Wochenschrift
    |August 2, 2014
    PubMed
    Summary

    This study assessed Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) neutralizing antibodies in Bavarian sow herds. EU-vaccinated sows showed the highest antibody titers, indicating EU-SNT reflects herd immunity and identifies immunity gaps.

    More Related Videos

    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
    09:14

    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

    Published on: January 26, 2019

    10.6K
    Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
    10:25

    Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

    Published on: June 5, 2021

    4.2K

    Related Experiment Videos

    Last Updated: Apr 26, 2026

    Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses
    05:49

    Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses

    Published on: November 21, 2023

    2.6K
    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
    09:14

    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

    Published on: January 26, 2019

    10.6K
    Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
    10:25

    Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

    Published on: June 5, 2021

    4.2K

    Area of Science:

    • Veterinary Virology
    • Immunology
    • Swine Health

    Context:

    • Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses significant challenges to swine production globally.
    • Two main genotypes, European (EU) and United States (US), exist, with available attenuated live-vaccines for both.
    • Understanding herd immunity is crucial for effective PRRSV control strategies.

    Purpose:

    • To evaluate the level of neutralizing antibodies against PRRSV genotypes in Bavarian sow herds.
    • To assess the correlation between vaccination status, PRRSV genotype detection, and antibody titers.
    • To determine the diagnostic value of ELISA and serum neutralization tests (SNT) in assessing herd immunity.

    Summary:

    • A cross-sectional study analyzed sera from 38 Bavarian sow herds, categorizing them by vaccination status (EU, US, or non-vaccinated).
    • EU-vaccinated sows exhibited the highest EU-SNT titers, suggesting the EU-SNT effectively reflects herd immunity against the EU vaccine virus.
    • ELISA showed high reactivity in US-vaccinated herds with EU-PRRSV detection, but its value is limited to certifying PRRSV-free herds, while EU-SNT indicates herd immunity gaps.

    Impact:

    • The EU-SNT is a valuable tool for assessing herd immunity levels against PRRSV, particularly identifying deficiencies in protection.
    • ELISA's utility is primarily for confirming PRRSV-free status rather than assessing active immunity.
    • Findings contribute to optimizing PRRSV vaccination and management strategies in swine herds.